Abstract:This paper introduced the preparation method of roxburgh rose collagen tablets. The Guizhou fresh roxburgh roses processed into fruit pieces with a series of procedures received vacuum freeze drying and pulver－ ization to get roxburgh roses freeze-dried powder. Auxiliary additives such as collagen powder， grape seed ex－ tract， mannitol， xylitol， microcrystalline cellulose， starch， magnesium stearate， etc. were added. The subse－ quent productions were completed after procedures of sieving， mixing， granulating， drying， granulating， total blending， tabletting， packaging， testing and so on. After the orthogonal test， the optimized formula and produc－ tion processes were finally established.